Tablets, a common form of oral medication, may develop visible or internal defects as a result of improper manufacturing processes and equipment or suboptimal formulations. Catching these tablet defects — whether manually or via an automated visual inspection system — helps ensure high product quality and consumer confidence. This article will highlight common tablet defects, […]
Manufacturers have the choice of direct compression, wet granulation, and dry granulation in tablet production. Direct compression incorporates the processes of mixing and processing a tablet’s formulation ingredients before using compression to generate tablets directly from powdered excipients or, specifically, active pharmaceutical ingredients (APIs). Manufacturers use direct compression to shorten operation times and reduce equipment […]
As tablets are the most common format for taking medicine orally, it can be surprising that tablet production processes still present many quality control challenges for manufacturers. Tablets have the potential for a variety of defects, from external surface flaws to internal imperfections in the product’s layers that result from formulation issues. Visible and non-visible […]
Tablets need to be compressed just the right amount for accurate dosage and volume delivery. At the same time, the equipment must deliver fast processing, minimal product waste, and the right level of automation for the specific product and volume. This blog post will discuss the tooling selection process for tablet presses. Importance of Tooling […]
Dwell time plays an important role in tablet manufacturing processes. Understanding how dwell time works can help improve the results of the manufacturing process for many types of tablet products. In this blog post, we’ll discuss what dwell time is, its impact on tablet compression, and how certain tools can affect dwell time in these […]
At Fette Compacting, we are the world’s leading provider of integrated industrial tablet production solutions. In addition to designing and manufacturing tablet press units, we offer comprehensive support services to help keep equipment running effectively and efficiently, so our customers save time and money. In the following article, our experts highlight four tips to help […]
In tablet compression, it’s important to know and have a good understanding of the different machine parts involved. Here we’ll provide an overview of some key parts that are used in tablet compression applications. Critical Tablet Compression Machine Parts There is a wide variety of integral parts used for tablet compression, including: Tablet Compression Machine […]
In recent years, multi-layer tablets have risen in popularity as an efficient and cost-saving oral drug delivery method. These tablets consist of two or more separate layers/levels of drugs pressed together into a single-dosage form. Each drug layer/level may have a different release rate. This quality is beneficial if the person needs to take two […]
Tablet tooling generally encompasses tablet punches and dies. Tooling stations traditionally consist of an upper punch, a lower punch, and a die, which are responsible for size, shape, and identification markings of tablets while meeting the specified requirements for dosage uniformity, production efficiency, and aesthetic appearance. Tablet compression tooling follows two standards that are recognized […]
Fette Compacting’s turret and tooling designs make it possible to rapidly produce high-quality steel products. This is in part due to the strict standards we follow—we match our heat-treating process with various formulations, which greatly extends the working life of our tableting tools. In addition to applied heat treatments, we only use high-quality, high-alloy materials […]
